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Tuna Tettrazini is a hearty casserole. The easy homemade cream sauce is the key to this delicious dish that’s perfect for an easy weeknight dinner or entertaining. Double (or triple) the batch because you’ll definitely want enough for leftovers!
I received complimentary product, but the opinions are all mine.
This post and recipe card updated February 15, 2020

I don’t recall my parents ever making tuna recipes when I was a kid, so I don’t think I ever ate it. As a young adult, I ate it primarily in tuna fish sandwiches, and then I had a few staple lunch recipes so I always have tuna in the pantry.
Tuna is light, healthy, delicious and versatile, and you could even eat it straight out of the can. My go-to is solid white albacore tuna, because of the thick, meaty chunks.
I was that kid…my food couldn’t touch on the plate, and if it did I wouldn’t eat the part that was touching. Even so, I still liked casseroles and other stuffed, baked goodness.
I have a few tuna recipes on the blog, but I’m always looking for new twists, and that’s how I created Tuna Tettrazini
WHY THIS RECIPE WORKS
- You can make it ahead, and bake as needed
- It’s great for weeknight dinner, potlucks, and leftovers
- The easy homemade cream sauce adds incredible flavor

When I knock it out of the park with a new dish, I dance around the kitchen. And yes, this Tuna Tettrazini made me dance!
TIPS FOR THE PERFECT TUNA TETTRAZINI
I use Solid White Albacore Tuna because I really like the meaty chunks and hearty texture. Sustainability matters, so I always look for wild-caught tuna.
Make your own cream sauce. Yes, you could use store-bought, but it is very easy to make your own and it’s so much more flavorful. It takes a little patience, but it’s well worth it.
I use Homemade Vegetable Broth, milk and heavy cream as the base of the sauce. I’ve used almond milk and regular milk interchangeably. If you use store-bought broth, look for low sodium or no salt added.
Traditional tuna casserole only uses mushrooms and peas. I add carrots, celery, red onion and garlic in my Tuna Tettrazini. I also saute the vegetables first, to slightly soften them and bring out the flavors.
Use a sturdy pasta to stand up to the other ingredients. I use Bucatini. It’s a long pasta like spaghetti, but thicker and it has a hole down the middle.
Use Whole Nutmeg and grate it into the skillet. Freshly grated nutmeg has so much more flavor than ground.
I like to top the Tuna Tettrazini with Corn Flake Crumbs right before baking. You could also use regular bread crumbs.

STEP BY STEP INSTRUCTIONS
Break dry Bucatini noodles into thirds. In a large pot of salted boiling water, cook for 10 minutes. They will be VERY al dente, but will finish cooking in the oven. Drain and set aside.
Melt butter in a large skillet. Add carrots, celery, and onion, and cook for 5 minutes. Add garlic and cook for 1 minute. Next, add mushrooms and cook for 5 minutes. Remove vegetable mixture and set aside.
Add remaining butter and whisk over medium-low heat until melted. Add flour and whisk constantly until smooth and no lumps remain

Slowly pour in the broth, whisking constantly for 2 minutes. Add milk and whisk for 2 minutes. Add heavy cream and whisk for 3-4 minutes, until thickened.

Sprinkle in salt, pepper, onion powder, garlic powder, and dried thyme. Grate nutmeg directly into the skillet. Return sauteed vegetables to the skillet and also add frozen peas.

Stir everything together, and add drained tuna and fresh-grated Parmesan

Stir well to combine all the ingredients, and add Bucatini

Use tongs to combine everything together. Transfer mixture to an 8×8 baking dish. Top with corn flake crumbs
Bake in a 375-degree oven for 30 minutes, until bubbling. Serve immediately

FREQUENTLY ASKED QUESTIONS
Can you substitute half and half for the heavy cream? You can, but then you’ll definitely need to use regular milk. The sauce won’t thicken enough with almond milk.
Can you use frozen mixed vegetables instead of fresh? Yes, you can. This recipe uses frozen peas already, so you would just omit the sauteed vegetables at the beginning.
Can you use a different style of tuna? You can use your favorite tuna. Make sure to only use tuna packed in water, not in oil.
What about leftovers? Make a double batch, and keep the rest in an airtight container in the fridge. Leftovers will last 5-7 days.
MORE DELICIOUS TUNA RECIPES
MORE CASSEROLES & COMFORT FOOD
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Tuna Tettrazini
Tuna Tettrazini is a hearty casserole. The easy homemade cream sauce is the key to this delicious dish that’s perfect for an easy weeknight dinner or entertaining. Double (or triple) the batch because you’ll definitely want enough for leftovers!
Ingredients
- 2 5oz cans Solid White Albacore Tuna in Water, drained and flaked with a fork
- 4 ounces Bucatini pasta, broken into thirds
- 2 Tablespoons butter
- 1/4 cup carrots, diced
- 1/4 cup celery, diced
- 1/4 cup red onion, diced
- 2 cloves garlic, minced
- 4 ounces baby portobello mushrooms, quartered
- 1/3 cup frozen peas
- 1/4 cup fresh grated Parmesan cheese
- 1/4 cup Corn Flake crumbs
CREAM SAUCE
- 2 Tablespoons butter
- 2 Tablespoons all-purpose flour
- 1/2 cup vegetable broth (I use homemade)
- 1/2 cup milk
- 1/2 cup heavy cream
- 1/2 teaspoon sea salt
- 1 teaspoon fresh cracked black pepper
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- 1 teaspoon dried thyme
- 1/2 teaspoon fresh-grated nutmeg
Instructions
- Preheat oven to 375 degrees
- Break dry Bucatini into thirds. Add to a large pot of salted boiling water and cook for 10 minutes. WILL BE VERY AL DENTE. Drain and set aside
- Melt 2 Tablespoons butter in a large skillet. Add carrots, celery, and onion and cook for 5 minutes, until softened slightly. Add garlic and cook for 1 minute. Next, add mushrooms and cook for 5 minutes. Transfer vegetable mixture to a bowl
- Add remaining 2 Tablespoons butter to the skillet, and melt. Add flour and whisk constantly over medium-low heat, until well combined and smooth.
- Slowly add vegetable broth, whisking constantly for 2 minutes. Add milk and whisk for 1 minute. Add heavy cream and whisk for 3-4 minutes, until thickened. Turn off heat.
- Add salt, pepper, onion powder garlic powder, and dried thyme. Grate nutmeg directly into the skillet. Add sauteed vegetables and frozen peas. Mix well to combine.
- Add drained tuna and Parmesan, and mix together.
- Add pasta, and combine well. I use tongs for easier mixing.
- Transfer mixture to an 8x8 baking dish. Top with corn flake crumbs
- Bake in oven for 30 minutes. Top with just a little more Parmesan cheese immediately before serving
Notes
MILK: I've used regular milk and almond milk interchangeably.
BROTH: I use homemade. If you use store-bought, look for low sodium or no salt added.
Use whole nutmeg and grate it into the skillet. It has so much more flavor this way.
If you don't have corn flake crumbs, you can substitute breadcrumbs.
FREQUENTLY ASKED QUESTIONS
Can you substitute half and half for the heavy cream? You can, but then you’ll definitely need to use regular milk. The sauce won’t thicken enough with almond milk.
Can you use frozen mixed vegetables instead of fresh? Yes, you can. This recipe uses frozen peas already, so you would just omit the sauteed vegetables at the beginning.
Can you use a different style of tuna? You can use your favorite tuna. Make sure to only use tuna packed in water, not in oil.
What about leftovers? Make a double (or triple) batch, and keep the rest in an airtight container in the fridge. Leftovers will last 5-7 days. I eat individual portions as leftovers, and reheat them in the microwave.
Nutrition Information:
Yield: 4Amount Per Serving: Calories: 526Total Fat: 28gSaturated Fat: 17gTrans Fat: 1gUnsaturated Fat: 9gCholesterol: 109mgSodium: 867mgCarbohydrates: 37gFiber: 3gSugar: 5gProtein: 31g
Nutrient values are estimates only. Variations may occur due to product availability and food preparation. Nutrition may vary based on methods of preparation, origin and freshness of ingredients, etc
Farrukh Aziz
Monday 4th of October 2021
This recipe bridges together my favorite ingredients, and I love how easy it is to make! The flavors were fantastic, thanks! :)
Karyl
Monday 18th of October 2021
Thank you so much Farrukh! I'm so glad you enjoyed it, and thanks for stopping by
Linda
Saturday 2nd of October 2021
This recipe is a keeper! So perfect for busy weeknights and also so delicious that everyone asked for a second serving!
Karyl
Monday 18th of October 2021
Oh that's fantastic Linda! I'm so glad your family loved it.
Tyler
Friday 16th of July 2021
Hi! I've looked at a bunch of tuna tetrazzini and yours is by far the best sounding! I have one question however, I don't have heavy cream on hand and other recipes I've seen don't call for it. Do you think it would greatly alter the final result if I omitted it?
Karyl
Monday 18th of October 2021
You could swap it out for half and half. The sauce won't thicken up quite as well, but it will still be delicious.
Kay
Friday 28th of February 2020
Yes, something new my daughter will try! She loves tuna and pasta...... but hates tomatoes which this recipe doesn't have so perfect for her! Will let you know how we get on!
Karyl
Thursday 12th of March 2020
Sounds great Kay! Would love to hear how you like it
Catherine
Monday 23rd of April 2018
Oh this looks absolutely marvelous! Total comfort food right here...I would love this for dinner and I know my family would love this too. Great idea for tuna!